Brain Imaging and Artificial Intelligence

Theme 2

Development of neuroimaging, computational algorithms/artificial intelligence (AI) to identify biomarkers that can distinguish between healthy and disrupted eye and brain function. 

The game-changing ability to undertake in vivo brain or eye imaging in people with visual disfunction is exploited in Theme 2. Researchers use artificial intelligence (AI) and computational science to probe images of the retina and magnetic resonance imaging/functional magnetic resonance imaging (MRI/fMRI) brain scans to discover retinal and brain “signatures” that represent eye and/or brain diseases. One example is a recent finding that Google’s AI can predict what ophthalmologists cannot: whether a fundus photograph of a human eye belongs to a female or male patient. Our cluster members have expertise in AI, MRIs, and retinal imaging. Additional cluster members have expertise in Alzheimer’s disease, Parkinson’s disease, mood disorders, and cerebral vasculopathies.

Chair

Hee Yeon Im

Principal Investigators

Hye Jin ChungSilke Cresswell, Deborah Giaschi, Kendall HoHee Yeon ImKamyar Keramatian, Geoffrey Law, Da MaIvan Robert Nabi, Ipek Oruç, Helge Rhodin, Claire Sheldon, Miriam Spering

 
Publications and Articles
Publication Journal or Publisher Publication Date
The Pain in Dystonia Scale (PIDS)-Development and Validation in Cervical Dystonia Movement Disorders
Health system use and outcomes of urgently triaged callers to a nurse-managed telephone service for provincial health information after initiation of supplemental virtual physician assessment: a descriptive study CMAJ Open
Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced, inoperable pancreatic adenocarcinoma: a phase 1b observational study Cancer & Metabolism
Corrigendum to "Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics" "Antiviral Research 209 (2023)/105484" Antiviral Research
Virtual Care in CanMEDS 2025 Canadian Medical Education Journal
Eye movements during optic flow perception Vision Research
Embracing Monogenic Parkinson's Disease: The MJFF Global Genetic PD Cohort Movement Disorders
Reverse translation of artificial intelligence in glaucoma: Connecting basic science with clinical applications Frontiers in Ophthalmology
Discovery of lead natural products for developing pan-SARS-CoV-2 therapeutics Antiviral Research
Predicting time-to-conversion for dementia of Alzheimer's type using multi-modal deep survival analysis Neurobiology of Aging

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