Vision Restorative Therapies and Community-Grounded Care

Theme 4

Development of eye tissue substitutes as restorative therapies and exploration of community-grounded clinical services

This subcluster will undertake research in digital health and outreach studies, as we respectfully understand how certain groups have had inequitable access eye care, and the replacement of corneal tissues in patients with severe corneal dystrophies is limited by access to corneal tissues from post-mortem donors. One way to overcome this is to develop synthetic corneal tissues. 

Additionally, we will explore how partially-sighted people perceive the world through multi-sensory experiences. In particular, we will explore how partially-sighted people experience artistic creation through touch, smell, and hearing.

 

Chair

Alfonso Iovenio

Principal Investigators

Johan Foster, Alfonso Iovenio, Vikramaditya Yadav, Sonia Yeung, Lauren Ayton, Laura Yvonne Bulk, Geoffrey Law, Zaid Mammo, Sonia Yeung

 
Publications and Articles
Publication Journal or Publisher Publication Date
Recurrent herpes simplex virus keratitis associated with recombinant zoster vaccination Can J Ophthalmol. 2026 Sep 11 (online ahead of print).
Long-term clinical outcomes in chronic ocular graft-versus-host disease: a retrospective cohort study Eye
Standardized Classification System for Dysphotopsia Reporting Ophthalmology Glaucoma
Clinical Outcomes and Genomic Epidemiology of Multidrug-Resistant Methicillin-Resistant Staphylococcus aureus Keratitis American Journal of Ophthalmology
Glycan-encoded immune checkpoints and allorecognition: A mechanistic framework for transplantation and organ engineering Frontiers in Transplantation
Enzymatic ligation of anti-oxidant and anti-inflammatory sulfated polymers on endothelial surface for vascular protection in transplantation Biomedical Materials
Accuracy of intraocular lens power calculations in patients undergoing combined cataract surgery with Descemet stripping only: a pilot study Canadian Journal of Ophthalmology
Convergent and lineage-specific genomic changes shape adaptations in sugar-consuming birds Science. 2026
Development of a robust ion-selective membrane from sulfonated cellulose nanofibers for zinc-iodine redox flow batteries J Membr Sci. 2025
Artificial substitutes for Descemet's membrane - corneal endothelium complex: state of the art Experimental Eye Research
Bayesian Analysis of Valacyclovir Treatment Effect in ZEDS Ophthalmology
Potential roles of extracellular granzyme B in corneal and conjunctival diseases: A narrative review Experimental Eye Research
Endogenous production of nitric oxide by iNOS in human cells restricts inflammatory activation and cholesterol/fatty acid biosynthesis Free Radical Biology and Medicine
Perspectives of carriers of X-linked retinal diseases on genetic testing and gene therapy: A global survey Clin Genet
Closing the Gender Gap Among Canadian Ophthalmology Societies Semin Ophthalmol
Plant-based, aqueous, water-repellent sprays for coating textiles Soft Matter
Direct milling: Efficient, facile, and green method for processing fibrillated cellulose/polymeric nanocomposites with boosted thermomechanical and rheological performance Carbohydrate Polymers
Global impact of COVID-19 on corneal donor tissue harvesting and corneal transplantation Frontiers in Medicine
Spatially Directed Pyrolysis via Thermally Morphing Surface Adducts Angewandte Chemie
On the Roles of Cellulose Nanocrystals in Fiber Cement: Implications for Rheology, Hydration Kinetics, and Mechanical Properties ACS Sustainable Chemistry & Engineering

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