New mechanisms identified in the RIG-I antiviral signaling pathway through protease cleavge of 14-3-3ε
New mechanisms identified in the RIG-I antiviral signaling pathway through protease cleavge of 14-3-3ε
October 4, 2023
Congratulations to Dr. Leonard Foster, who is a contributing author a new research article, "Cleavage of 14-3-3ε by the enteroviral 3C protease dampens RIG-I-mediated antiviral signaling", published in the Journal of Virology. In this study, the authors identified 14-3-3ε as a direct target of enterovirus 3Cpro, and provided insights into the key regions of 14-3-3ε important for RIG-I signalling. Dr. Foster is a member of Subcluster 1: Molecular, Cellular and Eye.