New Review Reveals Insights into Purinergic Signalling via P2X Receptors and Unregulated ATP Release in Outer Retina: Implications for Age-Related Macular Degeneration

July 11, 2023
Dr. Joanne Matsubara

New review by Dr. Joanne Matsubara and colleagues improves our understanding of the mechanisms that drive AMD pathogenesis. ​​​​​This review paper, "Purinergic signaling via P2X receptors and mechanisms of unregulated ATP release in the outer retina and age-related macular degeneration", explores the interactions between purinergic signalling, ATP release, and known contributors to AMD pathogenesis including complement dysregulation and inflammasome activation. This work is published in Frontiers in Neuroscience. Dr. Matsubara is the Lead of the Research Excellence Cluster and a faculty member in Subcluster 1: Molecular, Cellular and Eye.

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Vision: Molecules, Behaviour, Society Research Excellence Cluster

Eye Care Centre (VGH) 2550 Willow Street
Vancouver, BC Canada V5Z 3N9
Website vision.ubc.ca

Research Excellence Clusters at UBC Vancouver is a joint initiative of the Provost and Vice-President, Academic, UBC Vancouver and the Vice-President, Research and Innovation. Funding support for the clusters is provided by Academic Excellence Funds – UBC Vancouver.

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